Monday, December 30, 2019

About Hapiness In The Play Death of a Salesman - Free Essay Example

Sample details Pages: 2 Words: 566 Downloads: 5 Date added: 2019/05/07 Category Society Essay Level High school Tags: Happiness Essay Did you like this example? Death of a Salesman was written in 1949 by Arthur Miller. In this famous American story, Miller depicts many scenarios within the Loman family regarding happiness, while others do not achieve it. He depicts this family as very dysfunctional, yet they all want nothing but the best for each other; success and happiness. Happiness is a state of contempt and well-being; physically and mentally. It is a feeling of peace within yourself. Being happy is vital in any persons life. Every human strives for happiness in their lives, even if it means that they must face and conquer challenges every so often. Willy, Biff, Happy, and Linda Loman all struggle with being truly contempt with their selves throughout the story. Willy Loman is a sixty-three-year-old salesman who cannot accept the truth. He constantly contradicts himself, which makes it very hard for him to be happy. He is an unstable man who is very insecure but uses his arrogance to try and cover his flaws such as his anxiet y. He has two main goals in life; to accumulate fancy materialistic items through his financial successes and to be liked in life. In the Death of a Salesman story, Willy believes that he is a respected and successful business man who has a positive influence on his sons lives. None of that is true. Biff knows his truth, and Happy is a truly successful businessman. Willy has a mental illness that causes him to have random and quick mood swings after he hallucinates. The hallucinations that Willy has are because he is searching for that happiness. Willy tries his hardest to hide his troubles and his anxiety by using defense mechanisms. Willy does not make enough money, nor is he liked let alone respected. Willy feels that he is a failure, and that is why he pushes his son Biff so hard. Unlike Willy, Biff Loman knows his truth. He can see his failures. He does not sit around and dream about something that he knows he is not able to achieve. Biff works with what is in front of him. Willy and Biff have the most poisonous relationship in this story. Willy told Biff through his childhood and early adulthood that if he has the looks and is well liked, and he can sweet talk his way regardless of the mechanisms used, such as lies, to get his way to achieve the success then he will be all set. Biff is Willys golden boy because he wants Biff to succeed, but he does not really care for Happys happiness. Oh, the irony that Happys name is Happy. The apple does not fall far from the tree. Happy is another Willy, but Happy is more successful than Willy. Happy has achieved the American dream; he has a good job and he is successful at his job. Even though he is financially set he struggles with realistic dreams such as getting rich quick when he knows that is not realistically possible. Happy knows he is better than Biff. Happy knows that he makes Willy proud, yet Willy pays more attention to Biff. If Willy could choose between Biff or Happy, he would always choose Biff. Even though Happy has accomplished so much financially in his business, he still feels lonely and most certainly unhappy. The Death of a Salesman teaches us many lessons. Willy is not one to live by. Don’t waste time! Our writers will create an original "About Hapiness In The Play Death of a Salesman" essay for you Create order

Sunday, December 22, 2019

Movie Review Full Metal Jacket - 1477 Words

Ronald Lee Emery, retired Staff Sergeant in the United States Marine Corps famous for his role in the movie Full Metal Jacket, once spoke about the call to battle saying, â€Å"It s my firm conviction that when Uncle Sam calls, by God we go, and we do the best that we can.† This is a simple yet powerful quote that embodies the feeling of duty to his country that provokes ordinary citizens to leave their everyday lives behind them and join the cause to protect their country. People enlist in the armed forces for a multitude of reasons but one reoccurring reason is a feeling of duty towards protecting ones country and in the case of the civil war this was a widely spread concept. The Union and Confederate soldiers possessed deeply held ideological, political, and patriotic convictions, which were the major reasons they enlisted, fought, and remained in the ranks. McPherson claims these ideals that motivated soldiers to join the army were a combination of duty to country as well as ones comrades, personal honor, and patriotism. Furthermore he claims that ideology and images of manhood were just as important to soldier motivation as group cohesion was. McPherson’s main argument about what motivated soldiers during the war breaks down the motivations of Civil War soldiers into three categories, the initial motivation or enlistment, the â€Å"sustaining† motivation, and finally combat motivation. While different, these three motivations were all intertwined and if not strong enough couldShow MoreRelatedMasculinity in Movies: Full Metal Jacket Essay753 Words   |  4 PagesMasculinity in Movies: Full Metal Jacket Stanley Kubrick’s Full Metal Jacket is a 1987 film which portrays the early careers of U.S. Marine Corps recruits preparing for the Vietnam War. Throughout the movie, one recognizes concepts covered in the TV and film analysis film class; specifically the issue of masculinity. The first part of this movie is an accurate representation of recruit training, enforcing the well known mantra â€Å"tear down then build up.† Present in this leadership style widelyRead MoreUSMC Then Now and Forever742 Words   |  3 Pagesour freedom then and still do today. The marines were established to protect what our four fathers had given us as Americans. The marines’ history is rich and full of wonderful triumphs. History is good and all but marines are more than their history. A famous speech tells it all, many of us have seen the movie Full Metal Jacket. In that movie we hear the rifleman’s creed. This is my rifle. There are many like it, but this one is mine. â€Å"My rifle is my best friend. It is my life. I must master it asRead MoreLanguage and Verbal Aggression1559 Words   |  6 Pagesgeneral explanation is also related to the topic of this assignment, that is the verbal aggression and specifically, face attack strategies the military depicted in movies that to some extent are present in real life. Life in the military, though full of hardship, challenges and strict discipline has proven, without its known shortcomings, to be formative in some cases, in others have contribute to the transformation of an everyday citizen into a soldier with an specific agenda. This is transformationRead More Stanley Kubrick Essays1577 Words   |  7 PagesFight, a sixteen-minute documentary on boxer Walter Cartier. This short film was later purchased by RKO for its This Is America series and played in theaters in New York. Encouraged by his success, Kubrick quit his job at Look and pursued filmmaking full-time. Soon, RKO assigned him to head a short film for their documentary series Pathe Screenliner. 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Almost every movie after Dr. Strangelove explored the dark sid e of human nature. Kubrick’s masterpiece 2001: A Space Odyssey, dealt with similar themes on the perils of technology and the evolution of man. Clockwork Orange, The Shining and Full Metal Jacket all explored the dark side of the human psyche and the violent nature of human beings. Alex is conditionally altered by scienceRead MoreEssay on Stanley Kubrick: Artist, Explorer and Pioneer3777 Words   |  16 Pagesachieve. It is also for that reason that he is not completely accepted by the film industry. Kubrick is a film renaissance man. He learns through doing, not watching. Upon a movie’s release he is involved with the entire process – has been known to review each location where the film will be shown (Ciment 225). His intensity is well known throughout the industry. Actors who work with Kubrick can expect to shoot the same scene up to 50 times before getting it just right. To say that he is a perfectionistRead MoreDiesel Marketing Strategy6776 Words   |  28 Pagesmultiplies the number of models. This range is more stylish, more offset and also more expensive than the last. The customer has virtually unlimited ability to customize, which attracts people.    o   Ã‚  Ã‚  Ã‚  Ã‚   Weight of suppliers:    Diesel has a policy of full integration of its value chain. Moreover Baylet Laurent, head of Diesel Stylelabs in Paris, explained that in his opinion, the strength of Diesel was its ability to maintain strong control of the entire product value chain (from production to pointRead MoreJazz Albums as Art Essay4662 Words   |  19 Pagesthese various lines of influence,(1) it has occurred to me that the jazz record album itself comprises a unique and significant item of American material culture (above all the covers but also the entire package, including the shellac, vinyl, and metal disks, the liner notes, and the sleeves and boxes that hold them). What follows here is a set of brief notes reflecting on the jazz record package or album as a unique multimedia creation deserving a comprehensive scholarly study and perhaps a museumRead MoreDy-No-Mite! Stereotypical Images of African Americans on Television Sitcoms4305 Words   |  18 Pagessame for the genre of African American sitcoms . Some critics believe that African Americans will never accept the images they see of themselves on network television. Like whites, African Americans on television sitcoms should be portrayed â€Å"in the full array of cultures that exist in our society.† Most likely, the majority of white television viewers see a sitcom as no more than 22 minutes of broadcast time and eight minutes of commercial intertwined with a laugh track. Nothing serious. But look

Friday, December 13, 2019

Bshs/382 Research and Statistics Dq’s Free Essays

string(187) " which an instrument measures the same way each time it is used under the same condition with the same subjects; in short, it is replicating an experiment and getting comparable results\." Week 1 DQ 1 1. Voluntary consent of the participant is absolutely essential. The subject must be capable of giving consent without coercion, and full responsibility for obtaining consent rests with the principal investigator. We will write a custom essay sample on Bshs/382 Research and Statistics Dq’s or any similar topic only for you Order Now 2. The experiment must be designed to bring forth results that will benefit society and that cannot be obtained in any other manner. 3. Human experimentation should be based on animal research results as well as knowledge of the natural course of events, disease, or problems. 4. All unnecessary mental or physical harm should be avoided. 5. When there is reason to believe that death or disabling injury may occur, no experiment should be conducted except, perhaps, when the experimenting physicians also serve as subjects. 6. The degree of risk should never exceed the humanitarian importance of the problem to be solved. 7. All precaution should be taken to protect subjects from even remote possibilities of injury or death. 8. Only qualified personnel should be allowed to conduct experiments. The principal investigator must be ready to terminate the experiment at any stage if it appears that injury or death will result. Research Techniques for the Health Sciences, Fourth Edition Chapter 4: Considering Ethics in Research Explain two basic principles for humane treatment of human subjects in research. Drawing on the course readings or a current news item, provide an example of a study in which ethical principles were not followed. How might study design have been improved in that case? The two basic principles for human treatment of human subjects in research most significant to me are, making sure all precaution is taken to protect subjects from even remote possibilities of injury or death, and allowing the subject to withdraw from the experiment at any time if a point is reached that may bring about physical or mental harm. It is important that we do not use humans in research as crash dummies, as if they are simply replaceable after harm and injury. It is only right to take all precautions and allow the human subject to change their mind about participating in the research. Ethical principles were not followed in the Tuskegee Syphilis Study found in our text. The human subjects were not fully aware of the study, and the purpose of the research was more so the subjects could die and they could perform an autopsy. Week 1 DQ 2 What are the advantages of using a mixed method approach to research? What are the challenges? Provide an example of how you have used (or, in the future, could use) this approach in your professional role. The strength of the research; 2) Use of multiple methods in a research helps to research a process or a problem from all sides; 3) Usage of different approaches helps to focus on a single process and confirms the data accuracy. A mixed research complements a result from one type of research with another one. This research does not miss any available data. The aim of a mixed method design is to summarize positive aspects of two approaches and produce a highly accurate data. When you use several methods in your research process, then you can use the strength of every type of information collection and minimize the weak points of every of both approaches. A mixed method approach of gathering and evaluation can increase the validity and accuracy of the information. The advantages of using a mixed method approach to research are having several different outcomes in the process of your research. What this does is allows the researcher to use the strengths from the information collected and minimize the weaknesses from the information collected. Using a mixed method approach can ultimately increase the accuracy and validity of the information. The challenges of using a mixed method approach will be that the time of researching will be extended. Extending the time of research could definitely be a challenge if there is a time frame to find results in. Depending on the purpose of the research, using a mixed method approach can be a waist of time. An example of using the mixed method approach was when I wanted to explore (qualitative objective) why people shop on-line. I conducted open-ended interviews (qualitative data collection) asking people why they shop on-line, and then I quantified the results by counting the number of times each type of response occurred (quantitative data analysis). Week 2 DQ 1 What is the difference between reliability and validity? Imagine that you are going to develop a new instrument for research in your field, using course readings, provide specific examples of how you might go about establishing its reliability and validity. (Make sure to cover at least one approach for determining reliability and one for determining validity. Reliability is, roughly, whether you could replicate an experiment and get comparable results – either because an individual’s responses are consistent (for example, their reaction times in a test are consistent when the test is carried out again), or the general overall results are consistent (for example, the average score on a test is the same or similar when carried out again on a comparable group) Validity is whether the construct you are using really measures what you are using it to measure. For example, if you devised a test to measure people’s self-esteem, does it really measure self-esteem, or something similar such as extraversion? Reliability refers to the ability to perform the same experiment and get the same results. Validity refers to the accuracy of those results. You could perform the same experiment many times and get the same results, but they may not be correct (if the experiment is flawed for example). This would be reliable, but not valid. Conversely, you could perform an experiment that yields accurate results once, but not when it is repeated. This would be accurate (one time anyway), but not reliable. Reliability is the consistency of the degree to which an instrument measures the same way each time it is used under the same condition with the same subjects; in short, it is replicating an experiment and getting comparable results. You read "Bshs/382 Research and Statistics Dq’s" in category "Free Research Paper Samples" For example, a second test measuring reaction time showing the same reaction times as the first test. Reliability is all about the ability to perform the same experiment and get the same results. Validity is whether the construct you are using really measures what you are using it to measure. It is essentially the strength of our conclusions, inferences or propositions. For example, a test measuring people’s confidence, does it really measure confidence, or something similar such as faith in something? Week 2 DQ 2 What are some of the advantages and disadvantages of survey research? Provide an example of survey research findings that were recently published in the news. First, briefly summarize the study design and findings. Second, based on what we have read about survey research, provide critical feedback on this study’s design or explain what additional information you would need to make a critical assessment of this study. Strengths: 9. Surveys are relatively inexpensive (especially self-administered surveys). 10. Surveys are useful in describing the characteristics of a large population. No other method of observation can provide this general capability. 11. They can be administered from remote locations using mail, email or telephone. 12. Consequently, very large samples are feasible, making the results statistically significant even when analyzing multiple variables. 13. Many questions can be asked about a given topic giving considerable flexibility to the analysis. 14. There is flexibilty at the creation phase in deciding how the questions will be administered: as face-to-face interviews, by telephone, as group administered written or oral survey, or by electonic means. 15. Standardized questions make measurement more precise by enforcing uniform definitions upon the participants. 16. Standardization ensures that similar data can be collected from groups then interpreted comparatively (between-group study). 17. Usually, high reliability is easy to obtain–by presenting all subjects with a standardized stimulus, observer subjectivity is greatly eliminated. Weaknesses: * A methodology relying on standardization forces the researcher to develop questions general enough to be minimally appropriate for all respondents, possibly missing what is most appropriate to many respondents. * Surveys are inflexible in that they require the initial study design (the tool and administration of the tool) to remain unchanged throughout the data collection. * The researcher must ensure that a large number of the selected sample will reply. * It may be hard for participants to recall information or to tell the truth about a controversial question. As opposed to direct observation, survey research (excluding some interview approaches) can seldom deal with â€Å"context. † Advantages of survey research could be cost efficiency since surveys are relatively inexpensive. Surveys are useful in describing the characteristics of a large population and not a lot of other methods of observation can provide this general capability. They can be administered fr om distant locations. Many questions can be asked about a given topic giving flexibility to the analysis. Disadvantages of survey research could be researchers being forced to develop general questions. Surveys are inflexible because they remain unchanged throughout the data collection. Also, with surveys the researcher must ensure that a large number of the selected sample will reply, otherwise the survey would not be sufficient. In the news there was a survey about homelessness in Santa Cruz County. A count and survey conducted by the United Way of Santa Cruz County and the nonprofit research firm Applied Survey Research, and it showed that the homeless population in Santa Cruz County has jumped 22 percent in two years. The survey design was cross-sectional. It asked several questions at one oint in time. The survey collected age, gender, race, and reason for being homeless. http://www. santacruzsentinel. com/opinion/ci_18565125 http://www. phc-santacruz. org/_pdfs/2011%20Santa%20Cruz%20Homeless%20Report%20-%20FINAL. pdf Week 3 DQ 1 How can you avoid bias when selecting samples for human services research? Imagine that you are going to design a survey that will be administered to consumers/clients in your field (e. g. , nursing home residents, youth mentors, single mothers); how would you go about sampling from this population in order to generate meaningful data? What might be some of the challenges in ending up with a representative sample? To avoid bias when selecting samples for human services research a diverse set of individuals should be chosen within the same community. Different ethnicities, different genders, equals different beliefs, backgrounds, and futures. Selecting individuals in this manner should avoid bias. Hypothetically I work for an organization that offers services to young and troubled girls, especially those who have been to juvenile hall. Schools and juvenile halls if permitted would be great places to begin my sampling. Schools and juvenile halls both have a diverse population where bias could be avoided. The barriers I could see myself running into would be getting the permission to survey the minors in the first place. The biggest barrier would be knowing what girls are considered troubled or not and who they are specifically to get only their feedback and not girls who are not considered troubled. Week 3 DQ 2 List different measures of variability discussed in the readings and, using your professional field, provide an example to illustrate the concept. If you were a manager looking at these measures of variability around some aspect of employee productivity, what may they tell you about an individual’s or team’s performance? The range is the most obvious measure of dispersion and is the difference between the lowest and highest values in a dataset. The range is based solely on the two most extreme values within the dataset. The range is simple to compute and is useful when you wish to evaluate the whole of a dataset. The standard deviation indicates how tightly the values in the dataset are bunched around the mean value. The standard deviation is the most vigorous measure of variability because it’s measuring how every value in the dataset varies from the mean. You must be careful when calculating the standard deviation to consider whether the entire population or a sample is being examined and to use the appropriate formula. If I were a manager looking at these measures of variability around some aspect of employee productivity, the range would point out the highs and the lows of the team performance. This would allow me to know my team’s strength and weakness, and then I would be able to work on ways to minimum the weaknesses in performance. Week 4 DQ 1 Based on the textbook readings, describe the â€Å"third variable problem† as it relates to correlation and provide an example of how you might see this played out in your own field. Week 4 DQ 2 How does hypothesis testing contribute to the scientific knowledge base? Based on the textbooks’ descriptions of hypothesis testing, provide an example of how you might implement this in your work. othesis is an edjucated guess an it is some time’s the closest we can get to the trueth of things we do not yet understand Scientists use a scientific method to investigate phenomena and acquire knowledge. They base the method on verifiable observation — i. e. , on empirical evidence rather than on pure logic or supposition — and on the principles of reasoning. [1] [2] Scientists propose explanations â⠂¬â€ called hypotheses — for their observed phenomena, and perform experiments to determine whether the results accord with (support) the hypotheses or falsify them. They also formulate theories that encompass whole domains of inquiry, and which bind supported hypotheses together into logically coherent wholes. They refer to theories sometimes as ‘models’, which usually have a mathematical or computational basis. [3] [4] determining the focus and direction of the research, it forces researcher to state the purpose of the activity, determines what variable are being studied and or considered and also it allows to a required operational definition of the variable that are being studied. Hypothesis testing is a must for any person to successfully test their studies and make sure there are no flaws. Hypothesis is an educated guess an it is some times the closest we can get to the truth on matters that we do not yet understand. Scientist base their method on verifiable observation rather than on logic. Hypothesis testing forces researchers to address the purpose of the activity while determining what variables need to be studied and also requires operational definition. How to cite Bshs/382 Research and Statistics Dq’s, Essays

Thursday, December 5, 2019

Cerebral Amyloid Angiopathy Samples †MyAssignmenthelp.com

Question: Discuss about the Cerebral Amyloid Angiopathy. Answer: Introduction Cerebral amyloid angiopathy has been referred to as congiphilic angiopathy, which is a form of angiopathy characterised by deposits of blood vessel walls in the blood nerval system, which shows the presence of abnormal of amyloid in the brain tissue, (Liu, et al., 2016). CAA has been associated with Alzheimers disease, which leads to bleeding of the brain which is often associated with dementia. The bleeding is often associated with bleeding of the lobe, (Walton et al., 2015). It often occurs through sporadic occurrence among the elderly population. CAA often has been categorized into two; Iceland and the British type. Medical management is to manage the symptoms. Speech and physical therapist have played significant role in managing the disease. Cystatin protein has often been associated with brain medical condition and plays crucial role in brain disorders. Cystatin gene is encoded with initial CST3 gene used as a biomaker, (Wuttkle et al., 2015). It has been associated with brain disorders. Mutations of the cystatin gene has been associated with cerebral amyloid angiopathy, it forms the basic susceptibility in causing Alzheimers disease, (Vella, 2015). The Gene Gene function and expression Cystatin gene is a protein form that encodes itself to humans to form CSTA gene. The gene forms super family forms like the sequences which form the normal cystatin like sequence which are active producing protease inhibitors. Some of the sequence often loses its inhibitory effect. Inhibitory families forms three groups which include the cystatin also referred to as stefins, type two cystatin and the kinigogens. The gene encodes the gene stefin which functions as cystatin protease inhibitor which forms the complex compound with papain and cathepsins B, H and L. They functions as a precursor of cell envelopes which are cornified in the keratinocytes and plays a role in epidermal development and maintenance, (Redecke et al., 2013). Gene structure Complete amino sequence of single polypeptide of human cystatin corresponds to the C DNA. The three characteristic structure of cystatin C is similar to homologous protein chicken cystatin. Studies have shown that the truncated form of cystatin C (A8) and of cystatin C variants produced at site directed mutagenesis. Of B18, H5, H6,L12, M7 and also identification of sequence of similarities of cystatin which have properties of peptide segments. Cystatin protease inhibitor, cystatin C forms amyloid deposits which accumulate in the cerebral haemorrhages with the amyloidosis Icelandic type, which leads to haemorrhages, (Xu et al., 2014). Cystatin is also associated with neurological a degenerative disease which is involved in pathogenic processes leading to amyloid deposits in the cerebral vasculature which is a condition which leads to cerebral haemorrhage in older patients. Gene locus Cystatin gene locus and conservation usefulness in animal models with the protein inhibitor has been found as expression of two sequence tags. The gene has been found to be located in the 2G3 chromosome area; it encodes the entire 141 amino acids. The protein has been found to be related to family 2 cystatins which lacks critical consensus sites for inhibition. The characteristics have been found in male reproductive system in mouse, (Miller et al., 2017). The protein Protein fucntion The protein nature of the cystatin C is non glycosylated basic protein which is a member of the cystatin super family of protease inhibitors. The structure is often illustrated with promotion and determined by the gene. The low molecular gene is in stable concentration of the protein which is determined by the glomerular filtrate rate of the individual. Protein description Cystatin C is a protein encoded with the form of CST3 gene which is mainly used as biomarker for kidney function. However more recent research has linked its role in predicting new onset or deteriorating cardiovascular disease. It also plays a significant orle on the brain disorders which often involves the amyloid protein. In humans, cells with nucleus produce cystatin C which produces chain of 120 amino acids. It fuses itself in the tissues and body fluids and acts as protein inhibitor, (Teyssou et al., 2013). Its molecular biology entails the super family proteins that contain the multiple cystatin like consequences. These members are active cystatin protease inhibitors while others have no inhibitory effects. The three inhibitory families include the type 1 cystatin proteins, type two cystatin and the kinogens. The type two are often associated with human fluids and secretions, where they appear to provide protective functions. Protein Properties The cystatin proteins are the class of cystatin proteins which are found in variety of human beings fluids, secretions. The gene is often found in the cystatin locus on the chromosome 20 which contains the majority of type two cystatin genes. It is encoded in the in extracellular inhibitor which is found in all organs. According to Akerblom et al., (2014), the CST3 gene contains the cystatin locus and comprises of 3 exons which have the coding regions and non coding regions in the gene. It contains the most extracellular inhibitor of cystatin protease. It is found highly in biological fluids and expressed in all organs of the human body. The three polymorphism in the promoter region lead to two variant. Cystatin C is a non glycosylated basic protein at the Ph of 9.3. The crystal structure of cystatin c is characterized by the short alpha helix and long helix alpha which is found across large anti parallel stranded beta sheet. Cystatin C forms dimmers which by exchanging the sub domains in the paired state. Cystatin C has been measured to having random sample of serum blood with red blood cells and clotting factors have been eliminated using immunoassays like the nephelometry. The test have proven to be more expensive to run Protein dysfunction and analysis Cystatin gene has been associated with neurologic disorders. A mutation in the cystatin 3 gene is responsible for the Icelander hereditary disease. It is a condition which predisposes the intracellular hemorrhage, stroke and other related diseases. These diseases are inheritable. It binds s the amyloidal b and leads to reduction of the aggregation and deposition. It is a potential target for Alzheimers diseases. These mutations have often been associated with amyloidal angiopathy. Majority of the studies done have majored on the CST3 Role of susceptibility in Alzheimers disease, (Wisment et al., 2015). Protein expression in the vascular wall of the smooth muscle proteins is often severely reduces in both atherosclerotic state and the aneurismal aortic lesions which is clearly observed in the aortic disease. The protein further has been shown to have antimicrobial effects which inhibit the replication of herpes simplex virus. Serum cystatin c is often measure with automated immunoassay. More sensitive changes of the GFR serum creatinin if often associated, (Stewart et al., 2014). The disease Description of the disease The cerebral amyloid angiopathy refers to the accumulation of the beta amyloid in the medial adventitia of the small and midsized arteries of the cerebral cortex and the lepromeninges. It is a factor of disorder in which the amyloid is deposited in the brain and is not linked to systemic amyloidal. CAA has always referred to one of the morphologic hallmarks of the Alzheimers disease. it is found in brains of the elderly people whose health state of the neurology is okay, (2-3). It is often asymptomatic; however it may lead to dementia, intracranial haemorrhage or transient events. The diagnostic guidelines of the disease have been clarified with the cerebral amyloid angiopathy, which associates the CAA with intracranial haemorrhage. The fouls levels of certainty in the diagnosis of the CAA are often considered as definite, probable supporting pathogenic evidence Molecular and cellular analysis The definite form of the CAA involves the full post-mortem examination which often reveals the lobar , cortical or the cortical sub cortical haemorrhage of severe case of CAA. Probable CAA has been found with supporting pathologic evidence. The clinical data of the pathologic tissue shows the haemorrhage of the characteristics and degree of amyloid deposition. The probable CAA shows the clinical data and magnetic resonance imaging which shows the multiple haematosis among patients over the age of 60 years. The aetiology of the disease often occurs in sporadic form. However genetic predispositions often exist, which include apoli protein subtypes which confer with different risk profiles. Most of the case of CAA is related with the intracranial haemorrhage which is spontaneous. Evidence have often linked data which suggest that the amyloid is produced in responds to the smooth muscle cells of the tunica media which damages the vessel walls, (Bai et al., 2016). Amyloid deposition is often complex and involves the key process of production of amyloid precursor proteins, processing of precursor proteins, aggregation of proteins and the fibrial formation. The impaired formation and accumulation of the soluble and the insoluble beta amyloid peptides have often underlie the occurrence of CAA shows the association between CAA and the Alzheimers disease. Amyloid fibrials often deposits itself in the cerebral vessels like in the case of amyloid CAA and plaques the parenchyma part of the brain, (Fitzpatrick et al., 2013). The accumulation dynamics of the clearance of the amyloid can be related to the impaired drainage from the peri- vascular basement membranes. The intestinal fluid and solute drain form the brain and the cervical lymph nodes in the capillary basements and the brain are powered by the pulsatile flow in the vessel, (5). The aetiology of the disease forms the basis of the hereditary brain cerebral haemorrhage with amyloidosis. The Dutch type hereditary cerebral haemorrhage with amyloidosis is often a disorder with complete penetration. Among individuals having this, 87 % have been found with ICH and 13% have infarcts. The amyloids have been in the cortical and leptimenngineal vessels; parenchyma neurofibrialliary which are not seen. The Icelandic type hereditary celebral haemorrhage has also shown autosomal dominant. The presences of the patient in the first episode of ICH in the third or fourth decade in some patients have shown underage clinical symptoms as young as age of 15 years. Amyloid angiopathy is more wide spread in this type than others which often involve arteries in the cerebrum, cerebellum and the brainstem part of the brain. The amyloid protein has shown itself as mutant gene of the cystatin protease inhibitor of cystatin C, (Carare et al., 2013). The haemorrhage in the protein has often been observed as the media for damages and the adventia of cortical and leptomengeal vessels which often leads to the thickening of the basal membrane. This process often results in the fibrinoid necrosis and the micro aneuryims formation which predisposes it to haemorrhage. The CAA has always been linked to the changes in the brain which include the lobar cerebral and the cerebella haemorrhage, leuko encephalopathy and plague depositions. It is often associated with the hypo-perfusion. Neuro pathology has been linked to mild CAA which affects the relatively smaller portions of the leptomengeal and superficial cortical vessels. Complete erosion of the arteries often occurs with only the endothelium surrounding the deposit remaining, which predisposes to haemorrhage. When viewed under electron microscope, it demonstrates the fibrils of the amyloid in the outer basement membrane in the initial stage of the CAA, (Boyle et al., 2015). Current and future treatment options More prevalence has been observed among the women more than men, with over the age of 65 years with risks increasing as the age advances. Patients with amyloid angiopathy of the cerebral often have increased risks of bleeding while taking medication such as the warfarin even when administered within the level of anticoagulation range. The vasculopathic change often predisposes these patients to small bleeds. The use of anticoagulant results in the enlargement of small haemorrhages what would otherwise remain asymptomatic. Withdrawing from these drugs of the family of anticoagulant agents has been shown to be prudent intervention to prevent the occurrence of patients with prior lobar haemorrhages. Strong evidence which provides the link between the CAA and the antithrombotic therapy is not sufficient. Treatment of hypertensions has been found to promote prevention of the recurrence of haemorrhage in the CAA. Transplantation has always been associated with the hereditary cause of CAA, mortality and the occurrence of cerebral haemorrhage and the dementia among patients who had transplants. 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