About Hapiness In The Play Death of a Salesman - Free Essay Example

Sample details Pages: 2 Words: 566 Downloads: 5 Date added: 2019/05/07 Category Society Essay Level High school Tags: Happiness Essay Did you like this example? Death of a Salesman was written in 1949 by Arthur Miller. In this famous American story, Miller depicts many scenarios within the Loman family regarding happiness, while others do not achieve it. He depicts this family as very dysfunctional, yet they all want nothing but the best for each other; success and happiness. Happiness is a state of contempt and well-being; physically and mentally. It is a feeling of peace within yourself. Being happy is vital in any persons life. Every human strives for happiness in their lives, even if it means that they must face and conquer challenges every so often. Willy, Biff, Happy, and Linda Loman all struggle with being truly contempt with their selves throughout the story. Willy Loman is a sixty-three-year-old salesman who cannot accept the truth. He constantly contradicts himself, which makes it very hard for him to be happy. He is an unstable man who is very insecure but uses his arrogance to try and cover his flaws such as his anxiet y. He has two main goals in life; to accumulate fancy materialistic items through his financial successes and to be liked in life. In the Death of a Salesman story, Willy believes that he is a respected and successful business man who has a positive influence on his sons lives. None of that is true. Biff knows his truth, and Happy is a truly successful businessman. Willy has a mental illness that causes him to have random and quick mood swings after he hallucinates. The hallucinations that Willy has are because he is searching for that happiness. Willy tries his hardest to hide his troubles and his anxiety by using defense mechanisms. Willy does not make enough money, nor is he liked let alone respected. Willy feels that he is a failure, and that is why he pushes his son Biff so hard. Unlike Willy, Biff Loman knows his truth. He can see his failures. He does not sit around and dream about something that he knows he is not able to achieve. Biff works with what is in front of him. Willy and Biff have the most poisonous relationship in this story. Willy told Biff through his childhood and early adulthood that if he has the looks and is well liked, and he can sweet talk his way regardless of the mechanisms used, such as lies, to get his way to achieve the success then he will be all set. Biff is Willys golden boy because he wants Biff to succeed, but he does not really care for Happys happiness. Oh, the irony that Happys name is Happy. The apple does not fall far from the tree. Happy is another Willy, but Happy is more successful than Willy. Happy has achieved the American dream; he has a good job and he is successful at his job. Even though he is financially set he struggles with realistic dreams such as getting rich quick when he knows that is not realistically possible. Happy knows he is better than Biff. Happy knows that he makes Willy proud, yet Willy pays more attention to Biff. If Willy could choose between Biff or Happy, he would always choose Biff. Even though Happy has accomplished so much financially in his business, he still feels lonely and most certainly unhappy. The Death of a Salesman teaches us many lessons. Willy is not one to live by. Don’t waste time! Our writers will create an original "About Hapiness In The Play Death of a Salesman" essay for you Create order

Movie Review Full Metal Jacket - 1477 Words

Ronald Lee Emery, retired Staff Sergeant in the United States Marine Corps famous for his role in the movie Full Metal Jacket, once spoke about the call to battle saying, â€Å"It s my firm conviction that when Uncle Sam calls, by God we go, and we do the best that we can.† This is a simple yet powerful quote that embodies the feeling of duty to his country that provokes ordinary citizens to leave their everyday lives behind them and join the cause to protect their country. People enlist in the armed forces for a multitude of reasons but one reoccurring reason is a feeling of duty towards protecting ones country and in the case of the civil war this was a widely spread concept. The Union and Confederate soldiers possessed deeply held ideological, political, and patriotic convictions, which were the major reasons they enlisted, fought, and remained in the ranks. McPherson claims these ideals that motivated soldiers to join the army were a combination of duty to country as well as ones comrades, personal honor, and patriotism. Furthermore he claims that ideology and images of manhood were just as important to soldier motivation as group cohesion was. McPherson’s main argument about what motivated soldiers during the war breaks down the motivations of Civil War soldiers into three categories, the initial motivation or enlistment, the â€Å"sustaining† motivation, and finally combat motivation. While different, these three motivations were all intertwined and if not strong enough couldShow MoreRelatedMasculinity in Movies: Full Metal Jacket Essay753 Words   |  4 PagesMasculinity in Movies: Full Metal Jacket Stanley Kubrick’s Full Metal Jacket is a 1987 film which portrays the early careers of U.S. Marine Corps recruits preparing for the Vietnam War. 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Bshs/382 Research and Statistics Dq’s Free Essays

string(187) " which an instrument measures the same way each time it is used under the same condition with the same subjects; in short, it is replicating an experiment and getting comparable results\." Week 1 DQ 1 1. Voluntary consent of the participant is absolutely essential. The subject must be capable of giving consent without coercion, and full responsibility for obtaining consent rests with the principal investigator. We will write a custom essay sample on Bshs/382 Research and Statistics Dq’s or any similar topic only for you Order Now 2. The experiment must be designed to bring forth results that will benefit society and that cannot be obtained in any other manner. 3. Human experimentation should be based on animal research results as well as knowledge of the natural course of events, disease, or problems. 4. All unnecessary mental or physical harm should be avoided. 5. When there is reason to believe that death or disabling injury may occur, no experiment should be conducted except, perhaps, when the experimenting physicians also serve as subjects. 6. The degree of risk should never exceed the humanitarian importance of the problem to be solved. 7. All precaution should be taken to protect subjects from even remote possibilities of injury or death. 8. Only qualified personnel should be allowed to conduct experiments. The principal investigator must be ready to terminate the experiment at any stage if it appears that injury or death will result. Research Techniques for the Health Sciences, Fourth Edition Chapter 4: Considering Ethics in Research Explain two basic principles for humane treatment of human subjects in research. Drawing on the course readings or a current news item, provide an example of a study in which ethical principles were not followed. How might study design have been improved in that case? The two basic principles for human treatment of human subjects in research most significant to me are, making sure all precaution is taken to protect subjects from even remote possibilities of injury or death, and allowing the subject to withdraw from the experiment at any time if a point is reached that may bring about physical or mental harm. It is important that we do not use humans in research as crash dummies, as if they are simply replaceable after harm and injury. It is only right to take all precautions and allow the human subject to change their mind about participating in the research. Ethical principles were not followed in the Tuskegee Syphilis Study found in our text. The human subjects were not fully aware of the study, and the purpose of the research was more so the subjects could die and they could perform an autopsy. Week 1 DQ 2 What are the advantages of using a mixed method approach to research? What are the challenges? Provide an example of how you have used (or, in the future, could use) this approach in your professional role. The strength of the research; 2) Use of multiple methods in a research helps to research a process or a problem from all sides; 3) Usage of different approaches helps to focus on a single process and confirms the data accuracy. A mixed research complements a result from one type of research with another one. This research does not miss any available data. The aim of a mixed method design is to summarize positive aspects of two approaches and produce a highly accurate data. When you use several methods in your research process, then you can use the strength of every type of information collection and minimize the weak points of every of both approaches. A mixed method approach of gathering and evaluation can increase the validity and accuracy of the information. The advantages of using a mixed method approach to research are having several different outcomes in the process of your research. What this does is allows the researcher to use the strengths from the information collected and minimize the weaknesses from the information collected. Using a mixed method approach can ultimately increase the accuracy and validity of the information. The challenges of using a mixed method approach will be that the time of researching will be extended. Extending the time of research could definitely be a challenge if there is a time frame to find results in. Depending on the purpose of the research, using a mixed method approach can be a waist of time. An example of using the mixed method approach was when I wanted to explore (qualitative objective) why people shop on-line. I conducted open-ended interviews (qualitative data collection) asking people why they shop on-line, and then I quantified the results by counting the number of times each type of response occurred (quantitative data analysis). Week 2 DQ 1 What is the difference between reliability and validity? Imagine that you are going to develop a new instrument for research in your field, using course readings, provide specific examples of how you might go about establishing its reliability and validity. (Make sure to cover at least one approach for determining reliability and one for determining validity. Reliability is, roughly, whether you could replicate an experiment and get comparable results – either because an individual’s responses are consistent (for example, their reaction times in a test are consistent when the test is carried out again), or the general overall results are consistent (for example, the average score on a test is the same or similar when carried out again on a comparable group) Validity is whether the construct you are using really measures what you are using it to measure. For example, if you devised a test to measure people’s self-esteem, does it really measure self-esteem, or something similar such as extraversion? Reliability refers to the ability to perform the same experiment and get the same results. Validity refers to the accuracy of those results. You could perform the same experiment many times and get the same results, but they may not be correct (if the experiment is flawed for example). This would be reliable, but not valid. Conversely, you could perform an experiment that yields accurate results once, but not when it is repeated. This would be accurate (one time anyway), but not reliable. Reliability is the consistency of the degree to which an instrument measures the same way each time it is used under the same condition with the same subjects; in short, it is replicating an experiment and getting comparable results. You read "Bshs/382 Research and Statistics Dq’s" in category "Free Research Paper Samples" For example, a second test measuring reaction time showing the same reaction times as the first test. Reliability is all about the ability to perform the same experiment and get the same results. Validity is whether the construct you are using really measures what you are using it to measure. It is essentially the strength of our conclusions, inferences or propositions. For example, a test measuring people’s confidence, does it really measure confidence, or something similar such as faith in something? Week 2 DQ 2 What are some of the advantages and disadvantages of survey research? Provide an example of survey research findings that were recently published in the news. First, briefly summarize the study design and findings. Second, based on what we have read about survey research, provide critical feedback on this study’s design or explain what additional information you would need to make a critical assessment of this study. Strengths: 9. Surveys are relatively inexpensive (especially self-administered surveys). 10. Surveys are useful in describing the characteristics of a large population. No other method of observation can provide this general capability. 11. They can be administered from remote locations using mail, email or telephone. 12. Consequently, very large samples are feasible, making the results statistically significant even when analyzing multiple variables. 13. Many questions can be asked about a given topic giving considerable flexibility to the analysis. 14. There is flexibilty at the creation phase in deciding how the questions will be administered: as face-to-face interviews, by telephone, as group administered written or oral survey, or by electonic means. 15. Standardized questions make measurement more precise by enforcing uniform definitions upon the participants. 16. Standardization ensures that similar data can be collected from groups then interpreted comparatively (between-group study). 17. Usually, high reliability is easy to obtain–by presenting all subjects with a standardized stimulus, observer subjectivity is greatly eliminated. Weaknesses: * A methodology relying on standardization forces the researcher to develop questions general enough to be minimally appropriate for all respondents, possibly missing what is most appropriate to many respondents. * Surveys are inflexible in that they require the initial study design (the tool and administration of the tool) to remain unchanged throughout the data collection. * The researcher must ensure that a large number of the selected sample will reply. * It may be hard for participants to recall information or to tell the truth about a controversial question. As opposed to direct observation, survey research (excluding some interview approaches) can seldom deal with â€Å"context. † Advantages of survey research could be cost efficiency since surveys are relatively inexpensive. Surveys are useful in describing the characteristics of a large population and not a lot of other methods of observation can provide this general capability. They can be administered fr om distant locations. Many questions can be asked about a given topic giving flexibility to the analysis. Disadvantages of survey research could be researchers being forced to develop general questions. Surveys are inflexible because they remain unchanged throughout the data collection. Also, with surveys the researcher must ensure that a large number of the selected sample will reply, otherwise the survey would not be sufficient. In the news there was a survey about homelessness in Santa Cruz County. A count and survey conducted by the United Way of Santa Cruz County and the nonprofit research firm Applied Survey Research, and it showed that the homeless population in Santa Cruz County has jumped 22 percent in two years. The survey design was cross-sectional. It asked several questions at one oint in time. The survey collected age, gender, race, and reason for being homeless. http://www. santacruzsentinel. com/opinion/ci_18565125 http://www. phc-santacruz. org/_pdfs/2011%20Santa%20Cruz%20Homeless%20Report%20-%20FINAL. pdf Week 3 DQ 1 How can you avoid bias when selecting samples for human services research? Imagine that you are going to design a survey that will be administered to consumers/clients in your field (e. g. , nursing home residents, youth mentors, single mothers); how would you go about sampling from this population in order to generate meaningful data? What might be some of the challenges in ending up with a representative sample? To avoid bias when selecting samples for human services research a diverse set of individuals should be chosen within the same community. Different ethnicities, different genders, equals different beliefs, backgrounds, and futures. Selecting individuals in this manner should avoid bias. Hypothetically I work for an organization that offers services to young and troubled girls, especially those who have been to juvenile hall. Schools and juvenile halls if permitted would be great places to begin my sampling. Schools and juvenile halls both have a diverse population where bias could be avoided. The barriers I could see myself running into would be getting the permission to survey the minors in the first place. The biggest barrier would be knowing what girls are considered troubled or not and who they are specifically to get only their feedback and not girls who are not considered troubled. Week 3 DQ 2 List different measures of variability discussed in the readings and, using your professional field, provide an example to illustrate the concept. If you were a manager looking at these measures of variability around some aspect of employee productivity, what may they tell you about an individual’s or team’s performance? The range is the most obvious measure of dispersion and is the difference between the lowest and highest values in a dataset. The range is based solely on the two most extreme values within the dataset. The range is simple to compute and is useful when you wish to evaluate the whole of a dataset. The standard deviation indicates how tightly the values in the dataset are bunched around the mean value. The standard deviation is the most vigorous measure of variability because it’s measuring how every value in the dataset varies from the mean. You must be careful when calculating the standard deviation to consider whether the entire population or a sample is being examined and to use the appropriate formula. If I were a manager looking at these measures of variability around some aspect of employee productivity, the range would point out the highs and the lows of the team performance. This would allow me to know my team’s strength and weakness, and then I would be able to work on ways to minimum the weaknesses in performance. Week 4 DQ 1 Based on the textbook readings, describe the â€Å"third variable problem† as it relates to correlation and provide an example of how you might see this played out in your own field. Week 4 DQ 2 How does hypothesis testing contribute to the scientific knowledge base? Based on the textbooks’ descriptions of hypothesis testing, provide an example of how you might implement this in your work. othesis is an edjucated guess an it is some time’s the closest we can get to the trueth of things we do not yet understand Scientists use a scientific method to investigate phenomena and acquire knowledge. They base the method on verifiable observation — i. e. , on empirical evidence rather than on pure logic or supposition — and on the principles of reasoning. [1] [2] Scientists propose explanations â⠂¬â€ called hypotheses — for their observed phenomena, and perform experiments to determine whether the results accord with (support) the hypotheses or falsify them. They also formulate theories that encompass whole domains of inquiry, and which bind supported hypotheses together into logically coherent wholes. They refer to theories sometimes as ‘models’, which usually have a mathematical or computational basis. [3] [4] determining the focus and direction of the research, it forces researcher to state the purpose of the activity, determines what variable are being studied and or considered and also it allows to a required operational definition of the variable that are being studied. Hypothesis testing is a must for any person to successfully test their studies and make sure there are no flaws. Hypothesis is an educated guess an it is some times the closest we can get to the truth on matters that we do not yet understand. Scientist base their method on verifiable observation rather than on logic. Hypothesis testing forces researchers to address the purpose of the activity while determining what variables need to be studied and also requires operational definition. How to cite Bshs/382 Research and Statistics Dq’s, Essays

Cerebral Amyloid Angiopathy Samples †MyAssignmenthelp.com

Question: Discuss about the Cerebral Amyloid Angiopathy. Answer: Introduction Cerebral amyloid angiopathy has been referred to as congiphilic angiopathy, which is a form of angiopathy characterised by deposits of blood vessel walls in the blood nerval system, which shows the presence of abnormal of amyloid in the brain tissue, (Liu, et al., 2016). CAA has been associated with Alzheimers disease, which leads to bleeding of the brain which is often associated with dementia. The bleeding is often associated with bleeding of the lobe, (Walton et al., 2015). It often occurs through sporadic occurrence among the elderly population. CAA often has been categorized into two; Iceland and the British type. Medical management is to manage the symptoms. Speech and physical therapist have played significant role in managing the disease. Cystatin protein has often been associated with brain medical condition and plays crucial role in brain disorders. Cystatin gene is encoded with initial CST3 gene used as a biomaker, (Wuttkle et al., 2015). It has been associated with brain disorders. Mutations of the cystatin gene has been associated with cerebral amyloid angiopathy, it forms the basic susceptibility in causing Alzheimers disease, (Vella, 2015). The Gene Gene function and expression Cystatin gene is a protein form that encodes itself to humans to form CSTA gene. The gene forms super family forms like the sequences which form the normal cystatin like sequence which are active producing protease inhibitors. Some of the sequence often loses its inhibitory effect. Inhibitory families forms three groups which include the cystatin also referred to as stefins, type two cystatin and the kinigogens. The gene encodes the gene stefin which functions as cystatin protease inhibitor which forms the complex compound with papain and cathepsins B, H and L. They functions as a precursor of cell envelopes which are cornified in the keratinocytes and plays a role in epidermal development and maintenance, (Redecke et al., 2013). Gene structure Complete amino sequence of single polypeptide of human cystatin corresponds to the C DNA. The three characteristic structure of cystatin C is similar to homologous protein chicken cystatin. Studies have shown that the truncated form of cystatin C (A8) and of cystatin C variants produced at site directed mutagenesis. Of B18, H5, H6,L12, M7 and also identification of sequence of similarities of cystatin which have properties of peptide segments. Cystatin protease inhibitor, cystatin C forms amyloid deposits which accumulate in the cerebral haemorrhages with the amyloidosis Icelandic type, which leads to haemorrhages, (Xu et al., 2014). Cystatin is also associated with neurological a degenerative disease which is involved in pathogenic processes leading to amyloid deposits in the cerebral vasculature which is a condition which leads to cerebral haemorrhage in older patients. Gene locus Cystatin gene locus and conservation usefulness in animal models with the protein inhibitor has been found as expression of two sequence tags. The gene has been found to be located in the 2G3 chromosome area; it encodes the entire 141 amino acids. The protein has been found to be related to family 2 cystatins which lacks critical consensus sites for inhibition. The characteristics have been found in male reproductive system in mouse, (Miller et al., 2017). The protein Protein fucntion The protein nature of the cystatin C is non glycosylated basic protein which is a member of the cystatin super family of protease inhibitors. The structure is often illustrated with promotion and determined by the gene. The low molecular gene is in stable concentration of the protein which is determined by the glomerular filtrate rate of the individual. Protein description Cystatin C is a protein encoded with the form of CST3 gene which is mainly used as biomarker for kidney function. However more recent research has linked its role in predicting new onset or deteriorating cardiovascular disease. It also plays a significant orle on the brain disorders which often involves the amyloid protein. In humans, cells with nucleus produce cystatin C which produces chain of 120 amino acids. It fuses itself in the tissues and body fluids and acts as protein inhibitor, (Teyssou et al., 2013). Its molecular biology entails the super family proteins that contain the multiple cystatin like consequences. These members are active cystatin protease inhibitors while others have no inhibitory effects. The three inhibitory families include the type 1 cystatin proteins, type two cystatin and the kinogens. The type two are often associated with human fluids and secretions, where they appear to provide protective functions. Protein Properties The cystatin proteins are the class of cystatin proteins which are found in variety of human beings fluids, secretions. The gene is often found in the cystatin locus on the chromosome 20 which contains the majority of type two cystatin genes. It is encoded in the in extracellular inhibitor which is found in all organs. According to Akerblom et al., (2014), the CST3 gene contains the cystatin locus and comprises of 3 exons which have the coding regions and non coding regions in the gene. It contains the most extracellular inhibitor of cystatin protease. It is found highly in biological fluids and expressed in all organs of the human body. The three polymorphism in the promoter region lead to two variant. Cystatin C is a non glycosylated basic protein at the Ph of 9.3. The crystal structure of cystatin c is characterized by the short alpha helix and long helix alpha which is found across large anti parallel stranded beta sheet. Cystatin C forms dimmers which by exchanging the sub domains in the paired state. Cystatin C has been measured to having random sample of serum blood with red blood cells and clotting factors have been eliminated using immunoassays like the nephelometry. The test have proven to be more expensive to run Protein dysfunction and analysis Cystatin gene has been associated with neurologic disorders. A mutation in the cystatin 3 gene is responsible for the Icelander hereditary disease. It is a condition which predisposes the intracellular hemorrhage, stroke and other related diseases. These diseases are inheritable. It binds s the amyloidal b and leads to reduction of the aggregation and deposition. It is a potential target for Alzheimers diseases. These mutations have often been associated with amyloidal angiopathy. Majority of the studies done have majored on the CST3 Role of susceptibility in Alzheimers disease, (Wisment et al., 2015). Protein expression in the vascular wall of the smooth muscle proteins is often severely reduces in both atherosclerotic state and the aneurismal aortic lesions which is clearly observed in the aortic disease. The protein further has been shown to have antimicrobial effects which inhibit the replication of herpes simplex virus. Serum cystatin c is often measure with automated immunoassay. More sensitive changes of the GFR serum creatinin if often associated, (Stewart et al., 2014). The disease Description of the disease The cerebral amyloid angiopathy refers to the accumulation of the beta amyloid in the medial adventitia of the small and midsized arteries of the cerebral cortex and the lepromeninges. It is a factor of disorder in which the amyloid is deposited in the brain and is not linked to systemic amyloidal. CAA has always referred to one of the morphologic hallmarks of the Alzheimers disease. it is found in brains of the elderly people whose health state of the neurology is okay, (2-3). It is often asymptomatic; however it may lead to dementia, intracranial haemorrhage or transient events. The diagnostic guidelines of the disease have been clarified with the cerebral amyloid angiopathy, which associates the CAA with intracranial haemorrhage. The fouls levels of certainty in the diagnosis of the CAA are often considered as definite, probable supporting pathogenic evidence Molecular and cellular analysis The definite form of the CAA involves the full post-mortem examination which often reveals the lobar , cortical or the cortical sub cortical haemorrhage of severe case of CAA. Probable CAA has been found with supporting pathologic evidence. The clinical data of the pathologic tissue shows the haemorrhage of the characteristics and degree of amyloid deposition. The probable CAA shows the clinical data and magnetic resonance imaging which shows the multiple haematosis among patients over the age of 60 years. The aetiology of the disease often occurs in sporadic form. However genetic predispositions often exist, which include apoli protein subtypes which confer with different risk profiles. Most of the case of CAA is related with the intracranial haemorrhage which is spontaneous. Evidence have often linked data which suggest that the amyloid is produced in responds to the smooth muscle cells of the tunica media which damages the vessel walls, (Bai et al., 2016). Amyloid deposition is often complex and involves the key process of production of amyloid precursor proteins, processing of precursor proteins, aggregation of proteins and the fibrial formation. The impaired formation and accumulation of the soluble and the insoluble beta amyloid peptides have often underlie the occurrence of CAA shows the association between CAA and the Alzheimers disease. Amyloid fibrials often deposits itself in the cerebral vessels like in the case of amyloid CAA and plaques the parenchyma part of the brain, (Fitzpatrick et al., 2013). The accumulation dynamics of the clearance of the amyloid can be related to the impaired drainage from the peri- vascular basement membranes. The intestinal fluid and solute drain form the brain and the cervical lymph nodes in the capillary basements and the brain are powered by the pulsatile flow in the vessel, (5). The aetiology of the disease forms the basis of the hereditary brain cerebral haemorrhage with amyloidosis. The Dutch type hereditary cerebral haemorrhage with amyloidosis is often a disorder with complete penetration. Among individuals having this, 87 % have been found with ICH and 13% have infarcts. The amyloids have been in the cortical and leptimenngineal vessels; parenchyma neurofibrialliary which are not seen. The Icelandic type hereditary celebral haemorrhage has also shown autosomal dominant. The presences of the patient in the first episode of ICH in the third or fourth decade in some patients have shown underage clinical symptoms as young as age of 15 years. Amyloid angiopathy is more wide spread in this type than others which often involve arteries in the cerebrum, cerebellum and the brainstem part of the brain. The amyloid protein has shown itself as mutant gene of the cystatin protease inhibitor of cystatin C, (Carare et al., 2013). The haemorrhage in the protein has often been observed as the media for damages and the adventia of cortical and leptomengeal vessels which often leads to the thickening of the basal membrane. This process often results in the fibrinoid necrosis and the micro aneuryims formation which predisposes it to haemorrhage. The CAA has always been linked to the changes in the brain which include the lobar cerebral and the cerebella haemorrhage, leuko encephalopathy and plague depositions. It is often associated with the hypo-perfusion. Neuro pathology has been linked to mild CAA which affects the relatively smaller portions of the leptomengeal and superficial cortical vessels. Complete erosion of the arteries often occurs with only the endothelium surrounding the deposit remaining, which predisposes to haemorrhage. When viewed under electron microscope, it demonstrates the fibrils of the amyloid in the outer basement membrane in the initial stage of the CAA, (Boyle et al., 2015). Current and future treatment options More prevalence has been observed among the women more than men, with over the age of 65 years with risks increasing as the age advances. Patients with amyloid angiopathy of the cerebral often have increased risks of bleeding while taking medication such as the warfarin even when administered within the level of anticoagulation range. The vasculopathic change often predisposes these patients to small bleeds. The use of anticoagulant results in the enlargement of small haemorrhages what would otherwise remain asymptomatic. Withdrawing from these drugs of the family of anticoagulant agents has been shown to be prudent intervention to prevent the occurrence of patients with prior lobar haemorrhages. Strong evidence which provides the link between the CAA and the antithrombotic therapy is not sufficient. Treatment of hypertensions has been found to promote prevention of the recurrence of haemorrhage in the CAA. Transplantation has always been associated with the hereditary cause of CAA, mortality and the occurrence of cerebral haemorrhage and the dementia among patients who had transplants. This study could not be generalized due to the small sample size it targeted, (Mattila et al., 2014). The medical process of cerebral amyloid angiopathy is untreatable, thus management of CAA related intracranial haemorrhage has been found to be identical to the standard management of CH. Cerebral drug developed for the managed of the CAA to reduce the amyloid formation and deposition has not been widely utilised due to safety concern. References kerblom, A., Eriksson, N., Wallentin, L., Siegbahn, A., Barratt, B.J., Becker, R.C., Budaj, A., Himmelmann, A., Husted, S., Storey, R.F. and Johansson, ., 2014. Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study. American heart journal, 168(1), pp.96-102. Bai, H. X., Zhou, H., Tan, X., Huang, X., Yang, L. 2016. Cerebral amyloid angiopathy as an etiology for cortical superficial siderosis: an unproven hypothesis. American Journal of Neuroradiology, 37(3), E25-E25. Boyle, P. A., Yu, L., Nag, S., Leurgans, S., Wilson, R. S., Bennett, D. A., Schneider, J. A. 2015. Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons. Neurology, 85(22), 1930-1936. Carare, R. O., Hawkes, C. A., Jeffrey, M., Kalaria, R. N., Weller, R. O. 2013. cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy. Neuropathology and applied neurobiology, 39(6), 593-611. Fitzpatrick, A. W., Debelouchina, G. T., Bayro, M. J., Clare, D. K., Caporini, M. A., Bajaj, V. S., ... MacPhee, C. E. 2013. Atomic structure and hierarchical assembly of a cross- amyloid fibril. Proceedings of the National Academy of Sciences, 110(14), 5468-5473. Liu, C. C., Zhao, N., Yamaguchi, Y., Cirrito, J. R., Kanekiyo, T., Holtzman, D. M., Bu, G. 2016. Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid- clearance and aggregation in Alzheimers disease. Science translational medicine, 8(332), 332ra44-332ra44. Mattila, O. S., Sairanen, T., Laakso, E., Paetau, A., Tanskanen, M., Lindsberg, P. J. 2014. Cerebral amyloid angiopathy related hemorrhage after stroke thrombolysis: Case report and. Redecke, L., Nass, K., DePonte, D. P., White, T. A., Rehders, D., Barty, A., ... Williams, G. J. 2013. Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser. Science, 339(6116), 227-230. Stewart, G. D., OMahony, F. C., Laird, A., Rashid, S., Martin, S. A., Eory, L., ... Mullen, P. 2014. Carbonic anhydrase 9 expression increases with vascular endothelial growth factortargeted therapy and is predictive of outcome in metastatic clear cell renal cancer. European urology, 66(5), 956-963. Teyssou, E., Takeda, T., Lebon, V., Boille, S., Doukour, B., Bataillon, G., ... Salachas, F. 2013. Mutations in SQSTM1 encoding p62 in amyotrophic lateral sclerosis: genetics and neuropathology. Acta neuropathologica, 125(4), 511-522. Walton, E., Hass, J., Liu, J., Roffman, J. L., Bernardoni, F., Roessner, V., ... Ehrlich, S. 2015. Correspondence of DNA methylation between blood and brain tissue and its application to schizophrenia research. Schizophrenia bulletin, 42(2), 406-414. Wiseman, F. K., Al-Janabi, T., Hardy, J., Karmiloff-Smith, A., Nizetic, D., Tybulewicz, V. L., ... Strydom, A. 2015. A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome. Nature reviews. Neuroscience, 16(9), 564. Wuttke, M., Schaefer, F., Wong, C. S., Kttgen, A. 2015. Genome-wide association studies in nephrology: using known associations for data checks. American Journal of Kidney Diseases, 65(2), 217-222. Xu, Y., Lindemann, P., Vega-Ramos, J., Zhang, J. G., Villadangos, J. A. 2014. Developmental regulation of synthesis and dimerization of the amyloidogenic protease inhibitor cystatin C in the hematopoietic system. Journal of Biological Chemistry, 289(14), 9730-9740.

A Pragmatic Marriage An Arranged Marriage English Literature Essay Essays

A Pragmatic Marriage An Arranged Marriage English Literature Essay Essays A Pragmatic Marriage An Arranged Marriage English Literature Essay Essay A Pragmatic Marriage An Arranged Marriage English Literature Essay Essay A matter-of-fact matrimony, really popularly known as an ordered matrimony is improbably common in many parts of the universe due to the common impression that trusting on the household to choose a possible partner is considered an advantage as they have old ages of wisdom and experience. The biggest plus point is that there is a knowing effort taken to fit the two households which includes the bride and groom on the broad runing parametric quantities of societal position, fiscal strength, background, educational chances and similar life styles every bit good as the physical visual aspects of the bride/groom as every household will desire to supply their offspring with protection, felicity and a unafraid life. This construct is thought to enormously increase the chance of the matrimony wining. On the contrary, the two people are complete aliens to each other when their matrimony is arranged by their household, therefore they might take clip to develop a degree of comfort and apprehension after matrimony. Geting to cognize each other before matrimony allows spouses to hold better regard and perceptual experience for each other s demands and desires. The advantage being that ample clip is achieved to research both the positive qualities and the negative qualities about each other and learn to cover with it, good in progress before matrimony therefore, making a satisfactory degree of comfort after matrimony effortlessly. A Love matrimonies are ideally based on many factors such as friendly relationship, regard, acquaintance and apprehension. Whereas in ordered matrimonies, one is forced to get married a alien with whom they have no history or bond with. A In most instances, the parents and relations are frequently domineering and seek to oblige their kid into a relationship he/ she does nt hold with. This creates a complicated state of affairs that may oblige the spouses to populate together womb-to-tomb in a matrimony that they are non con tent with. Besides popular love lore like Heer Ranjha and Sohni Mahiwal, India has ever followed a long tradition of ordered matrimonies. In the Indian society, love matrimonies are considered forbidden and Indian nuptialss are frequently associated with ordered matrimonies. Statisticss reveal that the divorce rate in India is merely 2 % as compared to the other parts of the universe such as United States with a divorce rate of 50 % . This can non be considered as a dependable statistical figure due to the fact that in India divorce is besides considered tabu. Therefore, whether they like being with their partner or non is nt the precedence. They are merely forced to remain in that relationship for the remainder of their lives. Womans have been known to go a victim and to remain on and bear a violent relationship for the interest of regard in society, household pride, parent s ego regard etc. Compromise and amendments form the foundation for a adult female in an ordered matrimony, chiefly becau se the married twosome does non hold any fixed impressions or outlooks from one another and they are non provided with any options. Womans continue to stay in sadistic relationships to keep their household s self-respect and regard and besides have to be improbably altruistic and resignation to his/her destiny. The adult female is regarded as a agency to the continuance of the household name every bit good as a willing slave to her hubby. Harmonizing to the Press Trust of India ( 2010 ) , Marriage can be forced to salvage honor, and adult females can be murdered for rejecting a forced matrimony and get marrieding a spouse of their ain pick who is non acceptable for the household of the miss. Therefore arranged matrimonies tend to be sexist. Bing in the twenty-first century, arranged matrimonies are now considered as an out-of-date impression. These yearss persons believe that no 3rd party can understand the workings of a individual s bosom other than them themselves. Love can besides overcast 1s mind and maintain them from seeing the mistakes of their possible mate doing it easier to compromise. In some parts of the universe, arranged matrimonies should be wholly outlawed as parents tend to take incorrect usage of it. Arranged matrimonies are considered as an illegal activity as this antediluvian method benefitted the are nt more than their progeny. Some parents arrange matrimonies for their kids within societal circles itself. Others did it for the pecuniary wagess offered by the other household. Therefore, ordered matrimony is sometimes considered as a concern trade between two households as they look into the belongings, wealth and position of the household in the society and so finalise the relationship. Besides, some of these pre-planned matrimonies were used as a bargaining bit to discontinue a war between opposing household feuds. For illustration, throughout history as far back as the Romans and the Greeks, the war was sometimes averted by the matrimony of opposing civilizations as a means to peace and prosperity. In an ordered matrimony there are different kinds of force per unit areas faced by the miss and the male child to be fair-skinned and physically attractive. In India the immorality of dowery system, construct of fiting horoscopes and the caste and community issues, is sometimes taken to its extreme degrees and has greatly contributed to the statement against arranged matrimonies. Geting to cognize the partner before matrimony is what plays the most outstanding function in matrimony satisfaction, but carry throughing this demand depends on how much freedom we re given to cognize our opposite sex, before matrimony. Unlike our chances of the on-going passage from ordered matrimony to freedom of mate pick , place of parents in choosing kids s couples has non truly subsided. Harmonizing to a research done by Xu Xiaohe and Martin King Whyte ( 1990 ) , in twentieth century, China s Communist initiated back uping freedom of mate pick for immature people, while they were besides opposing dating civilization ( Xiaohe and Whyte, 1990 ) . Although this research entirely includes Chinese society during twentieth century, in-between easterners have faced instead similar state of affairs even in twenty-first century. When parents and the society support this type of scheme, parents can really set the rubric of ordered matrimony off, every bit good as maintaining their authorization vital. Meanwhile, they do nt allow their kids day of the month anyone, unless they meet the individual in individual. In this instance, they are really allowing their kids run into and cognize their hereafter partner before matrimony, so they have given them the chance to acquire to cognize that specific individual before matrimony, which could be considered an chance to fall in love or to develop bonds, but they are nt really allowing them know the opposite sex. They are so disquieted that they prefer to maintain their kids naA?ve, instead than allowing them risk their relationships, dating incorrect people. Some people may believe every bit long as you get to cognize your spouse before matrimony, it s adequate. But we believe in this instance, you have nt married the individual you were in love with ; you ve merely found a nice spouse to get married, because you were supposed to get married person finally. In ordered matrimony, the importance of acquiring to cognize your spouse before matrimony is wholly overlooked, which leads matrimonies to failure. Besides, when you do nt cognize how people from your opposite sex behave, think, talk or react to specific affairs, and what are the things that they care about, misinterpretation is the first load which will add to discontentment of your ordered matrimony. It s non deniable that the 1s who are forced to arranged matrimonies find ways to compromise with their partner ; because the standards of cognizing a matrimony as fulfilling are non merely limited to how twosomes get married. When twosomes are younger, they tend to measure degree of their matrimony satisfaction by their wealth or even political position. As clip goes by, even presence of expansive kids can impact their rating of their matrimony. For case, our ain grandparents got married when they did nt even cognize what matrimony is ; so they were neer asked about who they prefer to take as partner ; However, if you ask them whether they were satisfied with their matrimony or non, they would nt show discontentedness. Because if they had had dreams about matrimony, they had put them aside to make a via media with the life they were forced to hold, and if they did nt hold an thought of matrimony, they neer found out what love lucifer is. This does nt intend that twosomes who get mar ried with love lucifers ever stay every bit content as they d been at the first topographic point, but it does corroborate the fact that usually, the 1s who marry their love of their life, are more satisfied with their matrimony, than twosomes who are already content of their current life, but got married based on ordered matrimony. In the study done by by Xu Xiaohe and Martin King Whyte ( 1990 ) , it is stated that fluctuations of mate choice do non affect merely two classs, but a continuum from entire parental control to entire freedom of pick Along with this continuum. So fundamentally, when we oppose ordered matrimony, we re non merely against the effect of ordered matrimony, but besides against the strong authorization that parents have over the process of acquiring married. Arranged matrimony must be banned, because the political orientation behind this type of matrimony follows highly dogmatic forms sing parental authorization that make lives of twosomes suffering.

Crysts, Blasts and Clasts - Large Particles in Rocks

Crysts, Blasts and Clasts - Large Particles in Rocks Crysts, blasts and clasts are three simple words related to a very basic concept in geology: big particles in rocks. Actually, theyre pieces of words- suffixes- that are worth knowing about. They can be a little confusing, but a good geologist  can tell you the difference between all three.   Crysts The -cryst suffix refers to grains of a crystalline mineral. A -cryst can be a fully formed crystal like your typical garnet, or it can be an irregular grain that, even though its atoms are all in rigid order, has none of the flat faces that mark a crystal. The most important -crysts are the ones that are much larger than their neighbors; the general name for these is megacryst. As a practical matter, -cryst is used only with igneous rocks, although a crystal in metamorphic rocks may be called a metacryst. The most common -cryst youll see in the literature is the phenocryst. Phenocrysts sit in a groundmass of smaller grains like raisins in oatmeal. Phenocrysts are the defining feature of porphyritic texture; another way to say it is that phenocrysts are what define a porphyry. Phenocrysts generally consist of one of the same minerals found in the groundmass. (If they were brought into the rock from elsewhere, they may be called xenocrysts.) If theyre clean and solid inside, we may interpret them as being older, having crystallized earlier than the rest of the igneous rock. But some phenocrysts formed by growing around and engulfing other minerals (creating a texture called poikilitic), so in that case they werent the very first mineral to crystallize. Phenocrysts that have fully formed crystal faces are called euhedral (old papers may use the terms idiomorphic or automorphic). Phenocrysts with no crystal faces are called anhedral (or xenomorphic), and in-between phenocrysts are called subhedral (or hypidiomorphic or ​hypautomorphic). Blasts The -blast suffix refers to grains of metamorphic minerals; more precisely, -blastic means a rock texture that reflects the recrystallizing processes of metamorphism. Thats why we dont have a word megablast- both igneous and metamorphic rocks are said to have megacrysts. The various -blasts are described only in metamorphic rocks. Metamorphism produces mineral grains by crushing (clastic deformation) and squeezing (plastic deformation) as well as recrystallization (blastic deformation), so its important to make the distinction. A metamorphic rock made of -blasts of uniform size is called homeoblastic, but if megacrysts are also present it is called heteroblastic. The larger ones are usually called porphyroblasts (even though porphyry is strictly an igneous rock). So porphyroblasts are the metamorphic equivalent of phenocrysts. Porphyroblasts may be stretched out and erased as metamorphism continues. Some large mineral grains may resist for a while. These are commonly called augen (the German for eyes), and augen gneiss is a well-recognized rock type. Similar to -crysts, -blasts can display crystal faces in different degrees, but they are described with the words idioblastic, hypidioblastic and xenoblastic instead of euhedral or subhedral or anhedral. Grains inherited from an earlier generation of metamorphism are called paleoblasts; naturally, neoblasts are their younger counterpart. Clasts The suffix -clast refers to grains of sediment, that is, pieces of pre-existing rocks or minerals. Unlike -crysts and -blasts, the word clast can stand alone. Clastic rocks, then, are always sedimentary (one exception: a clast that is not yet wiped out in a metamorphic rock is called a porphyroclast, which, confusingly, is also classified as a megacryst). Theres a deep distinction drawn among clastic rocks between holoclastic rocks, like shale and sandstone, and pyroclastic rocks that form around volcanoes. Clastic rocks are made of particles ranging in size from microscopic to indefinitely large. The rocks with visible clasts are called macroclastic. Extra-large clasts are called phenoclasts- so phenoclasts, phenocrysts and porphyroblasts are cousins. Two sedimentary rocks have phenoclasts: conglomerate and breccia. The difference is that the phenoclasts in conglomerate (spheroclasts) are made by abrasion whereas those in breccia (anguclasts) are made by fracture. There is no upper limit to what can be called a ​clast, or megaclast. Breccias have the largest megaclasts, up to hundreds of meters across and larger. Megaclasts as big as mountains can be made by large landslides (olistrostromes), thrust faulting (chaoses), subduction (mà ©langes) and supervolcano caldera formation (caldera collapse breccias). Megaclasts are where sedimentology meets tectonics.

Market Research Proposal, With questionnaire (NO PRIMARY DATA Essay

Market Research Proposal, With questionnaire (NO PRIMARY DATA COLLECTION REQUIRED) - Essay Example A survey by Ernst and Young conducted amongst 23 matured and emerging market that were negatively affected by the credit crunch suggested that the customers of UK are seen to have low level of confidence on the banking system. About 63% has reported that their trust on the UK banks has completely fallen, whereas about 36% were completely dissatisfied (Flower, 2012). As all the banks generally deal with similar, undifferentiated category of products, so quality of the service becomes a primary weapon for winning the competition. The banks that display an excellent service quality are supposed to have a distinct marketing edge in terms of improved cross-selling rates, elevated revenues, better customer retention capabilities (Bennett and Higgins, 1988) and prolonged market share (Brown and Hedges, 1993). As defined by Ghobadian, Speller and Jones (1994) quality signifies how well the organizations cater to the requirement of the customers. The definition given by Deming (1986), Ishikaw a (1985), Feigenbaum (1986), and Juran et al. (1974) also fall under the same category. This approach suggests that the organization should first understand and determine the requirements of the customers and then meet unto them. The service quality can only be judged either during or after the consumption is made (Audhesh et al., 2005). The performance of the service provider is the primary source of value creation for the service that is signified as the service quality. It may be very trivial service performance by the service provider but is likely to create a huge impact on the perception of the customers about the service quality of the provider. Barclays Plc, one of the major banks of United Kingdom (UK) has been involved in the scandal of mis-selling of PPI due to which they had to pay huge compensation to the customers (PPI Claim Company, n.d.; BBC News, 2011). Lloyds Banking Group has also suffered problems with the Faster Payments System that is responsible for transferri ng of funds in and out of the accounts of the customers. This problem has given rise to a knock-on effect on the customers of the bank (BBC News, 2013a; Winch, 2013). Earlier in the year 2012 due to system failure the customer of Lloyds using TSB debit cards, online banking and ATM have also faced problem (BBC news, 2012b; Salmon, 2012). Same is the case with NatWest whose customers have also faced problems with online banking, cash withdrawal etc (BBC News, 2013b; Bachelor, 2013; Farrow, 2012). HSBC of UK has also reported the same problems in the year 2011 and 2012 (BBC News, 2012a; Rojas, 2012; Osborne and Bachelor, 2011). This situation has given rise to a growing concern for all these four banks that are eager to know what the expectations of their customers are. Thus the current study tries to find an answer to this question. Objectives The main objective of the research is to understand the perception of the customers towards banks as well as gaining knowledge about the wants of the customers. In this context the closely done study on the current status of the banking organizations suggests that the financial crisis as well as the recent

LABOUR MARKET POLICY The essay should be a maximum of 1400 words in

LABOUR MARKET POLICY The should be a maximum of 1400 words in length - Essay Example Since the agent represents the persona of the company, principles should selectively hire agents that can best represent their agenda. This relationship can be ideal when the agent is an expert in the field and displays allegiance to the principle. However, if overall goals aren’t uniformed then problems can arise. In order to minimize misunderstandings, informal or formal contracts, that explain what is expected of the agent, should be given to the agent and firmly enforced. The principle should ensure that vital language is inserted in the agreement to protect and promote the principle’s agenda. For corporations, which are your larger principles, human resource managers should be hired to maximize employee output. Authors David E Dimick and Victor V. Murray (1978: 611) in their article â€Å"Correlates of Substantive Policy Decisions in Organizations: The Case of Human Resource Management† defines human resource managers as personnel management which facilitate various organizational objectives. One responsibility of the human resource manager is the implementation of personnel practices that fit the specific needs of the employer. The human resource managers are directly responsible for the hiring of most qualified employees that display the most appropriate levels of capabilities. Thus the human resource manager should act in the best interest of the principle and formulate agency policy that benefits the behalf of the principle. Since human resource managers act as intermediaries between the corporate principle and agent, they should have in-depth knowledge of specific task demands. Knowing what is needed to ensure flow of operations, human resource managers should modify agency policy to include clear language to the agent of the expectations to their duties and expectations of the principle. According to the authors Lee G. Bolman and Terrence E. Deal

Software ownership Essay Example | Topics and Well Written Essays - 250 words

Software ownership - Essay Example The university was the pillar of the research in terms of financing. In addition, it had agreed to license the software for use in the research by Cyprotex. It was also argued that if Cyprotex had the software’s copyright, the University would not have been obligated to issue a license. The High Court and Appeal Court, therefore, found the university guilty. The High Court judge ruled that there was a misinterpretation of how the software was to be used. The contract had restrictions regarding the use of the research for commercial purposes. On the other hand, the Appeal Court based its judgement on a side agreement between the University and Cyprotex. The court held that Cyprotex’s employee was indeed an agent the University. The judge, therefore, held that the university should have been the owner of the software’s copyright. It would then be appropriate to hold the university accountable because it reserves the copyright to the

Hazards Of Sulphuric Acid And Caustic Soda

Hazards Of Sulphuric Acid And Caustic Soda A factory will be extended and it will consist of sulphuric acid and caustic soda and these two substances are hazardous substances which will be stored with propane which is a flammable substance and storage of these chemicals can pose various hazards to people and properties both on site and off site but theses hazards can be prevented or reduced as low as reasonably practical. Ai Sulphuric acid in concentrated form is highly irritating, toxic and corrosive to the tissue. Contact with this acid during leakage or spillage can rapidly destroy the tissue, and can cause severe burns, shock, collapse and other symptoms related to those of severe thermal burns, causing onsite hazard to the workers. The material used to construct the tank can cause hazard, according to HSE (2007), Sulphuric acid comes in contact with iron and some steel, hydrogen can be produced and trap quantities of these hydrogen can cause explosion resulting in onsite hazard. Leakages resulting from storage tank, tank truck can drain down the right way of embankment to the low grounds. If there is water flow, it can lead to water body containing acid causing off site hazard on the people that might drink from it, swim in the water, death or sickness off fishes and other water bodies. SCL (2002) Caustic soda can cause both onsite and offsite hazard, if caustic soda reacts with atmospheric carbon di oxide, blockages can be formed as a result of sodium hydroxide clumping.HSE (2007). During unloading of caustic soda if the lid of the tanks, flanks connected to the pipeline, the valves are opened or defected; ejection of caustic soda from the openings can result in accidents. Leakages of the tanks can also flow into the environment causing off site hazard. If this alkali comes in contact with the eyes it could lead to lowering or loss of vision, dermatitis or chronic eczema can affect skin. If the concentration is very high it can rapidly decompose affected tissue. Inflammation of the mouth, throat, oesophagus and stomach may occur if come in contact with NAOH. Japan Soda industry association (2006). As seen in sulphuric acid, this alkali can cause unusual fire and explosion hazard. If it comes in contact with water, moist air and certain metals. OSHA. Spillage of sulphuric acid and caustic soda can also result in slip and trip of workers. HSE (2003) Question Aii SULPHURIC ACID To reduce the risk of sulphuric acid the tank which the acid is stored should be constructed to appropriate standard by a specialist. Acid resistant material should be used to bund the acid stores. HSE (2007). Sulphuric acid residue and vapour are usually retained in empty containers. For this reason labelled safeguards should be observed until they have been thoroughly cleaned. The storage area should be correctly sited and provided with warning notices. Storage tanks should be segregated from incompatible material. The flooring should be constructed by acid resistant to prevent accidents such as slips and trip. The storage area must be secured and regular inspection should be carried out for the container and ancillaries in case of defect to avoid leakages Carson and Mumford (1988). The risk of sulphuric acid can be reduced by carrying out some precautions against exposure to the acid such as enclosing transfer, safety showers and eye wash facilities should be provided close to areas where exposure to the acid is possible. Employees and employers should be kitted up with personal protective equipment such as PVC plastic gloves with gauntlets, PVC plastic chemical suits, acid resistance boots, chemical goggles or face shield these personal protective equipment should be worn regularly especially when getting in contact with the acid and the whole body should be protected not wearing some and omitting others because contact of the acid with any part of the body can cause harm as seen above. Carson and Mumford (1988) Sulco is a chemical company in one of its bulletin described how a storage tank for sulphuric acid can be constructed and thus explains that carbon steel should be used in the construction of tanks and piping for concentrated sulphuric acid over 70% while the pumps and valves should be constructed with 316 stainless steel to avoid iron contamination and alloy 20 for prolonged life since they are subjected to wear. Concrete footing should be used to support the storage tank. The storage tank should be surrounded by a dike, dike material can be concrete or earth lined with compacted clay or can be a synthetic liner. The design and operation stages should be done with care to avoid liquid full sections of pipe between closed valves of which the hydrogen produced by steel corrosion causes dangerous pressures most especially in warmer weathers. On delivery of the sulphuric acid the competent person should ensure that the tank is big enough to contain the amount of sulphuric acid that is b eing delivered to avoid over filing. The person receiving the sulphuric acid should check the unloading connections of the truck to ensure that the material is unloaded into the proper storage tank to avoid explosion. SCL (2002) Unloading must be done by two people to reduce the possibility of accident and also in case of emergency the other can be of assistance and the facilities required for unloading should also be designed to reduce accidents location of the overflowing vent should be of interest, the vent should be directed away from buildings, isolation valves and air shut off valves into the dike. In cases of ruptured unloading hose, liquid isolation valve and air shut off valve should be far from the loading area so that the leak can be stopped quickly and safely. The truck driver should ensure that all equipment on his truck such as unloading hose is in good order. He and the person receiving should wear personal protective equipment and should be trained on proper actions to be carried out in case of spillage. During unloading of the acid, the truck should be wedged by wheel chocks to prevent movement while offloading. The ignition should also be off unless tractor air is needed. There should be po st warning signs, the operators should route traffic away from off loading areas. In an event of spill, ensure that the unloading area are covered or sealed for containment. The regulated air supply should be at normal of 30psi and maximum of 35psi. SCL (2002) From above it can be deduced that leakage can result in water body containing acid. To prevent this, steps should be taken to construct earth dikes downstream to contain the acid and water. If it is a frozen ground, back-hoe and front end loader will be necessary if a dam is needed, but if there is a high rate of flow through the area, damming may not be feasible, then a place farther downstream will be located where the contaminated water can be contained for neutralization before it reaches the main water course. The ph of the effluent liquid should be between 6.0-9.0 and the local regulation must be met before being sent for disposal. The tank truck should be made of 316 stainless steel, to prevent iron contamination. SCL (2002) CAUSTIC SODA Preventive measures should be carried out to avoid onsite and offsite hazard due to splash, leakage, outflow or penetration of caustic soda to the external environment. Due to its corrosive properties to avoid harm during working hours, a competent person should be employed to handle the alkali. He should be trained on the properties of caustic soda and various precautions on handling it. To avoid leakage of caustic soda, the competent person should be in charge in checking pipe opening and closing of valves, checking of the commencement and termination of the receiving and checking of the quantities received. Care should be carried out during loading and unloading of this alkali to the tanker to avoid mistake in transferring the alkali to the wrong tank to avoid exothermic reaction or explosion. The competent person should always wear personal protective equipment such as rubber gloves, rubber apron, work cap, protective goggle, cotton or synthetic fibre work, rubber boots and dust mask. Shower and face washing facilities should be provided close to where the caustic soda is being handled in case of any accident such as spillage or leakage. Japan Soda industry association (2006). Skin cream are also necessary for protecting the skin, they help wash contamination from skin and after work cream aids replacement of skin oil and this can also be carried out when working with propane and sulphuric acid.HSE (2006). To prevent leakages of caustic soda from flowing out of storage tank a spare tank should be installed to receive the alkali before emergency action is being carried out. Liquid bank such as earth fill, concrete, pit-like structure, pond and depression can also be constructed to accumulate the leaked caustic soda. These facilities tend to prevent harm from happening and the accumulated leaked caustic soda is then recovered and disposed. The alkali is disposed by neutralizing it with acid then wash it away it away with large quantity of water. The caustic soda water solution (water used for washing) should be neutralized before disposal to the river or sewage system to prevent polluting the river. Large quantity of leakage can be reduced by surrounding the leaked alkali with sand before disposing it as described above, small quantity of leaked liquid can be flushed with water or wiped off, and solid caustic soda can be recovered by scraping it together with sand or soda ash. The equipm ent that is being used to handle the caustic soda should be inspected periodically and the record should be retained. Erroneous operations can be prevented by taking certain measures like indicating name and directions of flow of the liquid, colour-coding and indication of the opening or closing direction of major valves and cocks. Checklist should be done during inspection of operating facilities and procedures. Japan Soda industry association (2006). Training should be carried on individuals involved in handling or working with the alkali, to prevent accident, they should be trained on proper usage of the personal protective equipment and first aid kit. HSE (2006) Caustic soda should be isolated from metals such as aluminium, tin, zinc because it corrodes them and hydrogen can be formed from this process and this can cause explosion. Caustic soda should be kept far from other chemicals, organic peroxides etc. From the above it can be deduced that not any material can be used to construct the storage tank for caustic soda. Steel can be used but it is safer to use a tank lined with rubber or alkali resistant synthetic resins. Defects and openings in the lid of the tanks, the body of the tanks, the flank connected to the pipeline and valves should be checked for by a competent person before injection of caustic soda into the tank. Japan Soda industry association (2006). Health monitoring should be carried on the workers working with propane, sulphuric acid and caustic soda. They should be asked to check their skin every six months for dryness and soreness and if these symptoms appears, the proper use of hand cream and PPE by the workers should be investigated HSE (2006). Question Bi According to Carson and Mumford (1988) leakages of propane can results hazard. Even small leakages can cause harm resulting in large volume of potential flammable gas. Propane is known to have anaesthetic properties; it is also known to cause depression of the central nervous system and can also be nauseating when inhaled. The density of propane is such that when released it can accumulate at low levels, filling valleys, sumps, ditches pits hugging contours of the ground, pipe-trenches, and propane is known to travel considerable distance causing offsite hazard when it comes in contact with a source of ignition can cause fire and explosion risk. Loss of liquid propane at temperature of 15oc causes vaporization of propane this is usually seen in nearly all propane released to the atmosphere this results in flammable vapour air cloud. This can cause onsite and offsite hazard. The propane can disperse harmlessly or it can ignite immediately in the factory (onsite hazard) if it comes in contact with an ignition source it can also drift until it reaches an ignition source then ignites, the cloud may burn with or without explosion, if the clouds is too rich to explode it may form a mobile fire ball. This can cause off site hazard. The radiant heat from this can cause burns on people and destroy properties and probably ignite combustible material depending on their distance to the fire ball. Debris can also be drawn in to the fireball by convection currents. Carson and Mumford (1988) explain that onsite and offsite hazards can also result from boiling liquid expanding vapour explosion (BLEVE). This result from failure of LPG vessel exposed to fire and mechanical damage this can be due to corrosion or by impact or due to over filling. The failure can result from either combination of weakening of part of the vessels exposed to fire and or excess pressure due to the effects of heat on the vessel content damages from BLEVEs arises from blast wave due to release of internal pressure, thermal radiation as a result of fire ball from massive burning of the contents of the vessels in the air which is preceded by ground flash, projection of fragments scattered over considerable distances due to violent rupture of the tank. Carson and Mumford (1988) explains that missiles usually travel alongside the direction which the end of the container is facing, but in some cases deviation can occur this can result in both onsite and offsite hazard. BLEVE ca n affect people and equipment onsite, passersby, onlookers, emergency services; road tankers can also be affected. BLEVEs can also affect road tankers during delivery if the tank suddenly rupture and blast and the blast are usually then followed by fireball. During transportation of hazardous material BLEVEs is the more severe and two types are known to affect tankers which is fired BLEVEs which has been discussed above and the cold BLEVE which can result from violent impact on the tank during traffic accident and other causes as seen in the storage tank. Accidental spill which can occur during delivery of propane can result to severe fire and explosion causing injuries and fatalities amongst off-road population resulting in off side hazard. Paltrinier, Gabriele, Menson et al (2009). Question Bii Risk assessment should be carried out to prevent off site and on site hazard as seen above and this should meet up with the standard of DSEAR. HSE (2009) As seen from above one main hazard that can affect both onsite and offsite is human error and this can be prevented by employing a trained and competent person who understands the job and the characteristics of the chemicals they are working with. During filling of vessels with propane, it is the duty of the competent person to ensure that the required free space is left in the vessels after addition of propane. He should also ensure that the storage vessels of propane should not be manifolded together and if manifolding is unavoidable then suitable non return valves should be fitted. Carson and Mumford (1988) Another hazard could result from the type of vessels in which the propane is stored. According to Carson and Mumford (1988) propane can be stored in any common metal (since its non corrosive) except from aluminium and external corrosion must be prevented. Non-metallic materials like rubber and certain plastics should be avoided. To ensure a good tank that will not give problem, advice on the type of materials to construct the storage vessels, valves, pipes, joints, seals etc. Should be given by the supplier and the plant should be designed, installed and maintained by a competent engineer using appropriate standard or codes. The storage vessels should be designed to endure the highest vapour pressure to be encountered during use; this can be due to highest temperature of exposure usually solar. The tank should be inspected for soundness, crack detection and weld integrity and this should be every five years. The positioning of the tank should also be considered, from above it can be deduced that some tanks are usually position below the ground level and other above the ground. Neither of the two ways can cause risk. To prevent the storage of propane below the ground level the tanks must be securely fixed and external protective coating should be provided to resist soil corrosion. If the tank is situated above the ground, the tank vessels should be elevated above the ground. It can be placed on the cement floor and the floor should be sloped away from the tank to prevent accumulation of propane in case of leakage or spillage. Installation are usually fitted with water drench systems to discharge water onto the vessels, this should be done in such a way that the water discharged onto the vessels gets to all the part of the vessels in case the vessels is threatened by direct flame impingement or radiant heat. This also prevents unnecessary discharge of vapour. This appliated could be from f ixed points such as drencher heads and monitors or mobile units spray nozzles. From above it can be deduced that BLEVEs occurs almost immediately hence these water spray stem should be automatic and should be less or equal to 600mm from the vessel surface to negate wind effects. Continuity of water supply should be at designed stage since the water discharge needs to be sustained for a prolonged period Carson and Mumford (1988). According to Landucci et al (2009) fired BLEVE on LPG road tankers during loading and unloading operations are the main cause of societal risk. Paltrinier, Gabriele, Menson et al (2009) explains that from previous studies it can be deduced that 85% of BLEVEs are thermally induced; hence prevention of fired BLEVEs may lead to reduction of risk related to LPG transportation. They further said that passive protection such as pressure relief valves and thermal coating can avoid fired BLEVE. The presence of thermal coating increases time to failure allowing time for effective mitigation actions by fire brigades. The employer or supervisors should ensure that the tank used in transporting the propane should have thermal coating. According to activities involving transportation of hazardous material (hazmat) is the main contributors to overall risk; hence reduction of risk can be achieved acting on hazardous material transport. A study carried out by Landucci et al (2009) also agrees with Paltrinier, Gabriele, Menson et al (2009) saying that coating produces effective protection of the tanks, it also increases the expected time for the tank to fail. They also concluded that introduction of fire protection coating may be a possible route to improve the safety of LPG distribution by road. The factory should be extended in such a way that the location of the storage tank will be far from the population in case of missiles and explosions hazard may not be formed. The end of the tank should be positioned from the population and the main building of the factory in case of missiles since missiles follows the direction of the end of the tank. Carson and Mumford (1988). According to HSE (1999) there are five steps to be considered when working with flammable substances, firstly ventilation: the area should be properly ventilated to enhance dispersal of liquids or gases in case of leaks, spills or release from any process. Secondly the storage and handling area should be free from ignition sources such as electrical equipment, smoking materials hot surfaces, open flames from heating equipment. Thirdly the chemical should be properly contained with the fourth step being elimination and this is not an option the fifth step by separating the chemical from other chemicals. These chemicals can be separated by physical barrier, wall or partition. If these steps above are carried out effectively where ever possible, the risk that can result the chemical will reduce especially that of propane. This can be summarised as ventilation, ignition, containment, exchange and separation (VICES), this five principle helps to ensure safe working conditions with flammab le substance such as propane. .

Biography of Ogden Nash Essay -- Papers

Ogden Nash was born on August 19, 1902 in Rye, New York and was raised there and in Savannah, Georgia. He received his education from St. George’s School in Rhode Island and he also attended Harvard University. His first published poem "Spring Comes to Murray Hill" was featured in the New Yorker Magazine in 1930. He subsequently joined the staff of the New Yorker Magazine in 1932. Throughout his career he published a total of nineteen books of poetry before his death on May 19, 1971. He manipulates the English language to fit in his poems to male jokes and keep his audience entertained. Nash says he gave up hope of becoming a serious poet and decided that it would be better to be a good bad poet than to be a bad good poet. Ogden Nash employs the use of humor and light hearted verse to talk about relationships, parenting, and life in general. Relationships were one of Ogden Nash’s most written about subjects. Relationships are a hard subject to write fun poetry about, but Nash makes it work like a charm by using funny generalizations and making them rhyme. He can do this like no other with any voice he feels needed. He uses serious, silly, and sincere tones in his work relating to relationships. In one poem in particular â€Å"u of an Ode to Duty† he tells about the confusing ever confusing relationship between men and women, and seems to take no obvious side in the matter. â€Å"On some occasions he writes in conventional modes, which means dropping the playful and the lightly satirical to write the pure lyric or to add a didactic note to the prevailing humorous tenor of his verse,† (Louis Hasley,2). Many of his poems about this topic are written with a personal feel, reading them makes you feel as... ... which he views on a daily basis. â€Å"The expression of wisdom, the incongruous sound effects, the comic deflation, all serve to endear the poet-fool to his audience,†(George Crandell,3). Through viewing Nash’s poetry I have learned that there needs to be a voice like his out in society to comment on nonsense, otherwise we would lose touch with our senses of humor. Works Cited Crandell, George W. Studies in American Humor, Vol. 7, 1989, pp.94-103. http://www.galenet.com/servelet/LitRC/ (10/26/1999) Frankenberg, Lloyd The New York Times Book Review, November 19, 1950, p.4 http://www.galenet.com/servelet/LitRC/ (10/26/1999) McCord, David The Saturday Review, February 10, 1951, p. 18 http://www.galenet.com/servelet/LitRC/ (10/26/1999) Hasley, Louis The Arizona Quarterly, Vol.27, 1971, pp. 241-250 http://www.galenet.com/servelet/LitRC/ (10/26/1999)